A practical guide to using and maintaining an LC/MS system§§The combination of liquid chromatography (LC) and mass spectrometry (MS) has become the laboratory tool of choice for a broad range of industries that require the separation, analysis, and purification of mixtures of organic compounds.§A Practical User's Guide provides LC/MS users with an easy-to-use, hands-on reference that focuses on the practical applications of LC/MS and introduces the equipment and techniques needed to use LC/MS successfully. Following a thorough explanation of the basic components and operation of the LC/MS system, the author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer for any given problem.
Chapter 1. Introduction to LC/MS.§§Chapter 2. The HPLC System.§§Chapter 3. The HPLC Column and Separation Modes.§§Chapter 4. HPLC and Column Maintenance.§§Chapter 5. Sample Preparation and Separations Development.§§Chapter 6. LC/MS Interfaces.§§Chapter 7. LC/MS Overview.§§Chapter 8. The Mass Analyzers.§§Chapter 9. Mass Spectrometer Maintence.§§Chapter 10. Application Areas for LC/MS.§§Chapter 11. Trace Analysis and LC/MS/MS.§§Chapter 12. Drug Discovery and Benchtop LC/MS.§§Chapter 13. Proteomics: LC/MALDI/TOF and MS/MS Libraries.§§Chapter 14. The Future of LC/MS.§§Appendix A: LC/MS Frequently Asked Questions.§§Appendix B: Solvents and Volatile Buffers for LC/MS.§§Appendix C: A Guide to Structure Interpretation.§§Appendix D: A Glossary of LC/MS Terms.§§Appendix E: LC/MS Selective Reading List.
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LC/MS: A Practical User's Guide focuses on practical applications of LC/MS in compound identification and analysis of trace impurities. Like Dr. McMaster's previous books, it is designed as an easy-to-use reference for people working with LC/MS systems. The book discusses empirical methods for optimizing the method, maintaining the instrumentation, and using mass spectral library databases for compound identification. It includes a CD-ROM with PowerPoint slides and Frequently Asked Questions meant to facilitate the use of the book for learning and teaching purposes.
Marvin C. McMaster is a consultant and adjunct professor of chemistry at the University of Missouri-St. Louis, teaching courses on HPLC, GC/MS, and laboratory computing. He is a former researcher and product developer for DuPont, Kraft Foods, and Ciba-Geigy, and previously worked as a technical sales support specialist for instrument companies.
€ 64,40