This is the authoritative introduction to the concepts and techniques of recombinant DNA research and their dramatic results. The book explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA. As a result, students learn how working scientists make real high-impact discoveries. Included are chapters on applications to human diseases, cancer, and forensics.
Foundations of DNAOverviewDNA is the Primary Genetic MaterialFrom DNA to ProteinBasics of Gene ExpressionBasic Tools of Recombinant DNAFundamental Features of GenesGetting DNA into Cells and OrganismsMoveable ElementsEpigeneticsRNAi Foundations of Genomics Overview Sequencing a Small Genome How the Human Genome was SequencedAnalyzing GenomesOverviewSequence AnalysisGenome-wide Functional AnalysisGenomic Approaches to Human BiologyHunting Human Disease Genes Cancer Genomics DNA and Justice